The analysis of genetic changes in solid tumors and hematological diseases permits a more exact classification of the disease and the use of targeted therapies. In addition, molecular pathology is employed for follow-up checkups during cancer therapy. Building on classic PCR tests, our lab uses next-generation sequencing (NGS), pyrosequencing, capillary electrophoresis and real-time PCR analysis. These methods allow detection of mutations and translocations in tumors and in hematological diseases. Another important molecular analysis area of application is the detection of pathogens such as bacteria or viruses in human specimens. Here molecular pathology is characterized by rapid pathogen diagnostics with high sensitivity.